1965 – Dr W.J. Cinden of Pennsylvania University and Dr E.D. Lambert of Lambert Laboratories published their findings in the anti-cancer effects of Agaricus Blazei Murill.
1975 – Department of Pharmacology of Tokyo University, Japan Cancer Association and Faculty of Agriculture of Shizuoka University started in-depth research on Agaricus Blazei Murill.
1980 – Report on the anti-tumor characteristics of Beta-Glucans extracted from Agaricus Blazei Murill was released in the 39th General Convention of Japan Cancer Association: They are effective against Sarcoma 180 Solid cancer and Ehrlich’s ascites carcinoma.
1985 – Report on the effect of Agaricus Blazei Murill in increasing macrophages and ehancing anti-cancer activity in mice was released in the 44th General Convention of Japan Cancer Association.
1994 – Scientists in Japan published report on their findings in the effect of Beta-1, 6 Glucan protein compounds extracted from Agaricus Blazei Murill in suppressing Meth-A Cancer and its mechanism.
1994 – Clinical Studies carried out by Lanzhou University of Medicine and Gansu Tumor Hospital in China in collaboration with Mie University in Japan proved that Agaricus Blazei Murill showed significant results in minimizing radiotherapy and chemotherapy side effects in cancer patients.
1995 – Scientists of UCLA released in the 9th World Convention of Immunology that their research reported that Agaricus Blazei Murill significantly enhancing the activities of Natural Killer Cells.
1997 – Agriculture College of Tokyo University released their finding that Agaricus Blazei Murill showed positive effects in the treatment of chronic diseases and conditions like high blood pressure, genetic skin problems and diabetes.
1999 – The US FDA Approved the enlisting of Agaricus Blazei Murill as an “Immune Enhancing” dietary supplement.
2001 – Scientists in Ehima University in Japan published their research findings that the anti-tumor activity of ergosterol extracted from Agaricus Blazei Murill might be due to direct inhibition of angiogenesis induced by solide tumors.
2003 – Memorial Sloan – Kettering Cancer Center in New York started a clinical study program on treating patients with metastatic neuroblastoma with Beta-Glucan.
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